A healthy bank is a bank that has sufficient capital, maintains good quality of its assets, is well managed and operated based on prudential principles, generates sufficient profits to maintain its business continuity, maintains liquidity so that it can fulfill its obligations at any time, and pays attention to risks associated risks. This study aims to examine the effect of CAR, NPL, BOPO and LDR on ROA of Conventional Commercial Banks recorded at the Financial Services Authority (OJK) for the period 2018-2020. The population and sample in this study were 77 conventional commercial banks with a sample of 231 observational data. The type of data used in this study is secondary data obtained from the annual financial statements of banks published in the Financial Services Authority (OJK) for the period 2018-2019.The sampling technique in this study uses a purposive sampling technique with three criteria. The analytical method used in this study is panel data regression analysis with the Eviews IO analysis tool. The results show that four variables, namely CAR have a positive and significant effect on ROA, NPL and BOPO have a negative and significant effect on ROA, and LDR has a positive influence. but not significant to ROA.