The purpose of this research is to determine the influence of spiritual motivation, psychological motivation, physiological motivation on employee performance through job satisfaction as a mediator variable at community health centers in Tanjungpinang City. The population in this study were all employees of the Tanjungpinang City Health Center, totaling 429 people with a sample of 207 respondents. The sampling technique used in this research is random sampling technique. This research uses variance-based Structural Equation lviodeling (SEM) techniques or better known as SEM PLS (Partial Least Square) and is assisted by SMART PLS 2.0.M3 software. Research results show that Spiritual Motivation has a positive and significant effect on employee performance. Psychological motivation has a positive and significant effect on employee pe1formance. Physiological A-fotivation has a positive and significant effect on employee performance. Job satisfaction has a positive and significant effect on employee performance. Spiritual motivation has a positive and significant effect on job satisfaction in community health centers throughout Tanjungpinang City. Psychological motivation has a positive and significant influence on job satisfaction in community health centers throughout Tarijungpinang City. Physiological motivation has a positive and significant influence on job satisfaction in community health centers throughout Tanjungpinang City. Spiritual motivation has a positive and significant influence through job satisfaction on employee performance. Psychological motivation has a positive and sign(ficant e_(fect through job satisfaction on employee performance. Physiological Motivation has a positive and significant effect through job satisfaction on employee performance.